![]() It is not a mucous-effecting mechanism because no mucous precipitate forms as with the metals. The toxic mechanism of PCP is possibly a biochemical interruption of oxidative phosphorylation. This is similar to the reaction of these metals observed in the gills of fish. The mechanism of toxicity for lead and zinc probably is the mucousmetal complex which precipitates on the body wall blocking the exchange of oxygen and carbon dioxide. The interactions of pH and these substances has been examined and discussed, and the importance of definition of the solution has been shown. The Tl m determined for zinc was 46.0 ppm at pH 7.5. For sodium pentochlorophenate (PCP) the Tl m was found to be 0.31 ppm at pH 7.5, 0.67 ppm at pH 8.6 and 1.4 ppm at pH 9.5. Their Tl m for lead was 49.0 pp, at pH 6.5 and 27.5 at a pH of 8.5. Their median tolerance limit (Tl m) for pH levels in modified Knop solution has been shown to be 5.8 to 9.7. Tubificid worms have been shown to be quite tolerant to toxic materials such as lead, phenol, and zinc.
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